1OYH
Crystal Structure of P13 Alanine Variant of Antithrombin
Summary for 1OYH
Entry DOI | 10.2210/pdb1oyh/pdb |
Related | 1E04 1NQ9 |
Descriptor | Antithrombin-III, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total) |
Functional Keywords | thrombin; inhibition; heparin analogue; serine protease inhibitor, blood clotting |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted, extracellular space: P01008 P01008 |
Total number of polymer chains | 2 |
Total formula weight | 100772.45 |
Authors | Johnson, D.J.D.,Huntington, J.A. (deposition date: 2003-04-04, release date: 2004-04-13, Last modification date: 2023-08-16) |
Primary citation | Johnson, D.J.D.,Huntington, J.A. The influence of hinge region residue Glu-381 on antithrombin allostery and metastability J.Biol.Chem., 279:4913-4921, 2004 Cited by PubMed: 14623882DOI: 10.1074/jbc.M311644200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.62 Å) |
Structure validation
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