1OY0

The crystal Structure of the First Enzyme of Pantothenate Biosynthetic Pathway, Ketopantoate Hydroxymethyltransferase from Mycobacterium Tuberculosis Shows a Decameric Assembly and Terminal Helix-Swapping

Summary for 1OY0

Entry DOI	10.2210/pdb1oy0/pdb
Descriptor	Ketopantoate hydroxymethyltransferase, MAGNESIUM ION (3 entities in total)
Functional Keywords	domain swapping, structural genomics, psi, protein structure initiative, tb structural genomics consortium, tbsgc, transferase
Biological source	Mycobacterium tuberculosis
Cellular location	Cytoplasm (Potential): P0A5Q8
Total number of polymer chains	5
Total formula weight	146947.96
Authors	Chaudhuri, B.N.,Sawaya, M.R.,Kim, C.Y.,Waldo, G.S.,Park, M.S.,Terwilliger, T.C.,Yeates, T.O.,TB Structural Genomics Consortium (TBSGC) (deposition date: 2003-04-03, release date: 2003-07-15, Last modification date: 2024-02-14)
Primary citation	Chaudhuri, B.N.,Sawaya, M.R.,Kim, C.Y.,Waldo, G.S.,Park, M.S.,Terwilliger, T.C.,Yeates, T.O. The Crystal Structure of the First Enzyme in the Pantothenate Biosynthetic Pathway, Ketopantoate Hydroxymethyltransferase, from M. tuberculosis Structure, 11:753-764, 2003 Cited by PubMed: 12842039 DOI: 10.1016/S0969-2126(03)00106-0 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation