1OXR

Aspirin induces its Anti-inflammatory effects through its specific binding to Phospholipase A2: Crystal structure of the complex formed between Phospholipase A2 and Aspirin at 1.9A resolution

1OXR の概要

• エントリーDOI: 10.2210/pdb1oxr/pdb
• 関連するPDBエントリー: 1LFF 1LN8
• 分子名称: Phospholipase A2 isoform 3, 2-(ACETYLOXY)BENZOIC ACID, CALCIUM ION, ... (4 entities in total)
• 機能のキーワード: o-acetyl-oxy phenol, complex, pla2, naja naja sagittifera, hydrolase
• 由来する生物種: Naja sagittifera
• 細胞内の位置: Secreted: P60045
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 13403.83

構造登録者

Singh, R.K.,Ethayathulla, A.S.,Jabeen, T.,Sharma, S.,Kaur, P.,Srinivasan, A.,Singh, T.P. (登録日: 2003-04-03, 公開日: 2004-04-27, 最終更新日: 2023-08-16)

• 主引用文献: Singh, R.K.,Ethayathulla, A.S.,Jabeen, T.,Sharma, S.,Kaur, P.,Singh, T.P.; Aspirin induces its anti-inflammatory effects through its specific binding to phospholipase A2: crystal structure of the complex formed between phospholipase A2 and aspirin at 1.9 angstroms resolution.; J.Drug Target., 13:113-119, 2005; PubMed: 15823962; DOI: 10.1080/10611860400024078

実験手法

X-RAY DIFFRACTION (1.93 Å)