1OX5

TOWARDS UNDERSTANDING THE MECHANISM OF THE COMPLEX CYCLIZATION REACTION CATALYZED BY IMIDAZOLE GLYCEROPHOSPHATE SYNTHASE

Summary for 1OX5

Entry DOI	10.2210/pdb1ox5/pdb
Related	1JVN 1OX4 1OX6
Descriptor	Imidazole glycerol phosphate synthase hisHF, NICKEL (II) ION, PHOSPHORIC ACID MONO-[5-({[5-CARBAMOYL-3-(5-PHOSPHONOOXY-5-DEOXY-RIBOFURANOSYL)- 3H-IMIDAZOL-4-YLAMINO]-METHYL}-AMINO)-2,3,4-TRIHYDROXY-PENTYL] ESTER, ... (4 entities in total)
Functional Keywords	complex cyclization; imidazole glycerophosphate synthase, transferase, lyase
Biological source	Saccharomyces cerevisiae (baker's yeast)
Total number of polymer chains	2
Total formula weight	124354.00
Authors	Chaudhuri, B.N.,Smith, J.L. (deposition date: 2003-04-01, release date: 2003-06-17, Last modification date: 2023-08-16)
Primary citation	Chaudhuri, B.N.,Lange, S.C.,Myers, R.S.,Davisson, V.J.,Smith, J.L. Towards Understanding the Mechanism of the Complex Cyclization Reaction Catalyzed by Imidazole Glycerophosphate Synthase:Crystal Structures of a Ternary Complex and the Free Enzyme Biochemistry, 42:7003-7012, 2003 Cited by PubMed: 12795595 DOI: 10.1021/bi034320h PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation