1OX5
TOWARDS UNDERSTANDING THE MECHANISM OF THE COMPLEX CYCLIZATION REACTION CATALYZED BY IMIDAZOLE GLYCEROPHOSPHATE SYNTHASE
Summary for 1OX5
Entry DOI | 10.2210/pdb1ox5/pdb |
Related | 1JVN 1OX4 1OX6 |
Descriptor | Imidazole glycerol phosphate synthase hisHF, NICKEL (II) ION, PHOSPHORIC ACID MONO-[5-({[5-CARBAMOYL-3-(5-PHOSPHONOOXY-5-DEOXY-RIBOFURANOSYL)- 3H-IMIDAZOL-4-YLAMINO]-METHYL}-AMINO)-2,3,4-TRIHYDROXY-PENTYL] ESTER, ... (4 entities in total) |
Functional Keywords | complex cyclization; imidazole glycerophosphate synthase, transferase, lyase |
Biological source | Saccharomyces cerevisiae (baker's yeast) |
Total number of polymer chains | 2 |
Total formula weight | 124354.00 |
Authors | Chaudhuri, B.N.,Smith, J.L. (deposition date: 2003-04-01, release date: 2003-06-17, Last modification date: 2023-08-16) |
Primary citation | Chaudhuri, B.N.,Lange, S.C.,Myers, R.S.,Davisson, V.J.,Smith, J.L. Towards Understanding the Mechanism of the Complex Cyclization Reaction Catalyzed by Imidazole Glycerophosphate Synthase:Crystal Structures of a Ternary Complex and the Free Enzyme Biochemistry, 42:7003-7012, 2003 Cited by PubMed: 12795595DOI: 10.1021/bi034320h PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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