1OX5

TOWARDS UNDERSTANDING THE MECHANISM OF THE COMPLEX CYCLIZATION REACTION CATALYZED BY IMIDAZOLE GLYCEROPHOSPHATE SYNTHASE

1OX5 の概要

• エントリーDOI: 10.2210/pdb1ox5/pdb
• 関連するPDBエントリー: 1JVN 1OX4 1OX6
• 分子名称: Imidazole glycerol phosphate synthase hisHF, NICKEL (II) ION, PHOSPHORIC ACID MONO-[5-({[5-CARBAMOYL-3-(5-PHOSPHONOOXY-5-DEOXY-RIBOFURANOSYL)- 3H-IMIDAZOL-4-YLAMINO]-METHYL}-AMINO)-2,3,4-TRIHYDROXY-PENTYL] ESTER, ... (4 entities in total)
• 機能のキーワード: complex cyclization; imidazole glycerophosphate synthase, transferase, lyase
• 由来する生物種: Saccharomyces cerevisiae (baker's yeast)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 124354.00

構造登録者

Chaudhuri, B.N.,Smith, J.L. (登録日: 2003-04-01, 公開日: 2003-06-17, 最終更新日: 2023-08-16)

• 主引用文献: Chaudhuri, B.N.,Lange, S.C.,Myers, R.S.,Davisson, V.J.,Smith, J.L.; Towards Understanding the Mechanism of the Complex Cyclization Reaction Catalyzed by Imidazole Glycerophosphate Synthase:Crystal Structures of a Ternary Complex and the Free Enzyme; Biochemistry, 42:7003-7012, 2003; PubMed: 12795595; DOI: 10.1021/bi034320h

実験手法

X-RAY DIFFRACTION (2.5 Å)