1OW3

Crystal Structure of RhoA.GDP.MgF3-in Complex with RhoGAP

1OW3 の概要

• エントリーDOI: 10.2210/pdb1ow3/pdb
• 分子名称: Rho-GTPase-activating protein 1, Transforming protein RhoA, MAGNESIUM ION, ... (6 entities in total)
• 機能のキーワード: complex, gtpase, gap, transition state, gene regulation-signaling protein complex, gene regulation/signaling protein
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Cytoplasm: Q07960; Cell membrane; Lipid-anchor; Cytoplasmic side: P61586
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 49759.36

構造登録者

Graham, D.L.,Lowe, P.N.,Grime, G.W.,Marsh, M.,Rittinger, K.,Smerdon, S.J.,Gamblin, S.J.,Eccleston, J.F. (登録日: 2003-03-28, 公開日: 2003-05-06, 最終更新日: 2023-08-16)

• 主引用文献: Graham, D.L.,Lowe, P.N.,Grime, G.W.,Marsh, M.,Rittinger, K.,Smerdon, S.J.,Gamblin, S.J.,Eccleston, J.F.; MgF(3)(-) as a Transition State Analog of Phosphoryl Transfer; Chem.Biol., 9:375-381, 2002; PubMed: 11927263; DOI: 10.1016/S1074-5521(02)00112-6

実験手法

X-RAY DIFFRACTION (1.8 Å)