1OV4

Crystal structure of human DHEA-ST complexed with androsterone

Summary for 1OV4

• Entry DOI: 10.2210/pdb1ov4/pdb
• Related: 1EFH 1J99
• Descriptor: Alcohol sulfotransferase, SULFATE ION, (3Beta,5alpha)-3-Hydroxyandrostan-17-one, ... (4 entities in total)
• Functional Keywords: alpha/beta fold, transferase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: Q06520
• Total number of polymer chains: 1
• Total formula weight: 35103.21

Authors

Chang, H.J.,Shi, R.,Rhese, P.,Lin, S.X. (deposition date: 2003-03-25, release date: 2004-02-17, Last modification date: 2023-08-16)

• Primary citation: Chang, H.J.,Shi, R.,Rehse, P.,Lin, S.X.; Identifying androsterone (ADT) as a cognate substrate for human dehydroepiandrosterone sulfotransferase (DHEA-ST) important for steroid homeostasis: structure of the enzyme-ADT complex.; J.Biol.Chem., 279:2689-2696, 2004; PubMed: 14573603; DOI: 10.1074/jbc.M310446200

Experimental method

X-RAY DIFFRACTION (2.7 Å)