1OQX

G-2 glycovariant of human IgG Fc bound to minimized version of Protein A called Z34C

Summary for 1OQX

• Entry DOI: 10.2210/pdb1oqx/pdb
• Related: 1L6X 1OQO
• Descriptor: immunoglobulin gamma-1 heavy chain constant region, Protein A Z34C, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: antibody, glycosylation, oligosaccharides, igg, peptide complex, z34c, protein a, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 58445.44

Authors

Raju, T.S.,Mulkerrin, M.G.,Parker, M.,De Vos, A.M.,Gazzano-Santoro, H.,Totpal, K.,Ultsch, M.H. (deposition date: 2003-03-11, release date: 2003-03-25, Last modification date: 2023-08-16)

• Primary citation: Raju, T.S.,Mulkerrin, M.G.,Parker, M.,De Vos, A.M.,Gazzano-Santoro, H.,Totpal, K.,Ultsch, M.H.; Impact of Fc Glycans on The Effector Functions Vary with the Antibody mechanism of Action; To be Published,

Experimental method

X-RAY DIFFRACTION (2.6 Å)