1OQO

Complex between G0 version of an Fc bound to a minimized version of Protein A called Mini-Z

1OQO の概要

• エントリーDOI: 10.2210/pdb1oqo/pdb
• 関連するPDBエントリー: 1L6X
• 分子名称: immunoglobulin gamma-1 heavy chain constant region, Minimized version of Protein A (Z34C), 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: antibody, glycosylation, oligosaccharides, igg, fc fragment, z34c, protein a, immune system
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 59258.21

構造登録者

Raju, T.S.,Mulkerrin, M.G.,Parker, M.,De Vos, A.M.,Gazzano-Santoro, H.,Totpal, K.,Ultsch, M.H. (登録日: 2003-03-10, 公開日: 2003-03-20, 最終更新日: 2023-08-16)

• 主引用文献: Raju, T.S.,Mulkerrin, M.G.,Parker, M.,De Vos, A.M.,Gazzano-Santoro, H.,Totpal, K.,Ultsch, M.H.; Impact of Fc Glycans on The Effector Functions Vary with the Antibody mechanism of Action; To be Published,

実験手法

X-RAY DIFFRACTION (2.3 Å)