1OQO
Complex between G0 version of an Fc bound to a minimized version of Protein A called Mini-Z
1OQO の概要
エントリーDOI | 10.2210/pdb1oqo/pdb |
関連するPDBエントリー | 1L6X |
分子名称 | immunoglobulin gamma-1 heavy chain constant region, Minimized version of Protein A (Z34C), 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total) |
機能のキーワード | antibody, glycosylation, oligosaccharides, igg, fc fragment, z34c, protein a, immune system |
由来する生物種 | Homo sapiens (human) 詳細 |
タンパク質・核酸の鎖数 | 4 |
化学式量合計 | 59258.21 |
構造登録者 | Raju, T.S.,Mulkerrin, M.G.,Parker, M.,De Vos, A.M.,Gazzano-Santoro, H.,Totpal, K.,Ultsch, M.H. (登録日: 2003-03-10, 公開日: 2003-03-20, 最終更新日: 2024-10-30) |
主引用文献 | Raju, T.S.,Mulkerrin, M.G.,Parker, M.,De Vos, A.M.,Gazzano-Santoro, H.,Totpal, K.,Ultsch, M.H. Impact of Fc Glycans on The Effector Functions Vary with the Antibody mechanism of Action To be Published, |
実験手法 | X-RAY DIFFRACTION (2.3 Å) |
構造検証レポート
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