1OOK

Crystal Structure of the Complex of Platelet Receptor GPIb-alpha and Human alpha-Thrombin

1OOK の概要

• エントリーDOI: 10.2210/pdb1ook/pdb
• 分子名称: Human Alpha Thrombin, PHE-PRO-ARG-Chloromethylketone, Platelet glycoprotein Ib alpha chain precursor, ... (8 entities in total)
• 機能のキーワード: leucine rich repeats, hydrolase
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 67930.65

構造登録者

Varughese, K.I.,Celikel, R.,Ruggeri, Z.M. (登録日: 2003-03-03, 公開日: 2003-07-22, 最終更新日: 2021-10-27)

• 主引用文献: Celikel, R.,McClintock, R.A.,Roberts, J.R.,Mendolicchio, G.L.,Ware, J.,Varughese, K.I.,Ruggeri, Z.M.; Modulation of alpha-thrombin function by distinct interactions with platelet glycoprotein Ibalpha; Science, 301:218-221, 2003; PubMed: 12855810; DOI: 10.1126/science.1084183

実験手法

X-RAY DIFFRACTION (2.3 Å)