1ONR

STRUCTURE OF TRANSALDOLASE B

1ONR の概要

• エントリーDOI: 10.2210/pdb1onr/pdb
• 分子名称: TRANSALDOLASE B (2 entities in total)
• 機能のキーワード: transferase, pentose shunt, multigene family
• 由来する生物種: Escherichia coli
• 細胞内の位置: Cytoplasm (Probable): P0A870
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 70255.93

構造登録者

Jia, J.,Huang, W.,Lindqvist, Y.,Schneider, G. (登録日: 1996-08-13, 公開日: 1997-03-12, 最終更新日: 2024-02-14)

主引用文献

Jia, J.,Huang, W.,Schorken, U.,Sahm, H.,Sprenger, G.A.,Lindqvist, Y.,Schneider, G.
Crystal structure of transaldolase B from Escherichia coli suggests a circular permutation of the alpha/beta barrel within the class I aldolase family.
Structure, 4:715-724, 1996

PubMed Abstract: Transaldolase is one of the enzymes in the non-oxidative branch of the pentose phosphate pathway. It transfers a C3 ketol fragment from a ketose donor to an aldose acceptor. Transaldolase, together with transketolase, creates a reversible link between the pentose phosphate pathway and glycolysis. The enzyme is of considerable interest as a catalyst in stereospecific organic synthesis and the aim of this work was to reveal the molecular architecture of transaldolase and provide insights into the structural basis of the enzymatic mechanism.

PubMed: 8805555
DOI: 10.1016/S0969-2126(96)00077-9

実験手法

X-RAY DIFFRACTION (1.87 Å)