1ONB
Solution structure of an engineered arginine-rich subdomain 2 of the hepatitis C virus NS3 RNA helicase
Summary for 1ONB
| Entry DOI | 10.2210/pdb1onb/pdb |
| Related | 1JR6 |
| Descriptor | helicase NS3 (1 entity in total) |
| Functional Keywords | alpha-beta-alpha, hydrolase |
| Biological source | Hepatitis C virus |
| Cellular location | Core protein p21: Host endoplasmic reticulum membrane; Single-pass membrane protein (By similarity). Core protein p19: Virion (By similarity). Envelope glycoprotein E1: Virion membrane; Single-pass type I membrane protein (Potential). Envelope glycoprotein E2: Virion membrane; Single-pass type I membrane protein (Potential). p7: Host endoplasmic reticulum membrane; Multi-pass membrane protein. Protease NS2-3: Host endoplasmic reticulum membrane; Multi-pass membrane protein (Potential). Serine protease NS3: Host endoplasmic reticulum membrane; Peripheral membrane protein (By similarity). Non-structural protein 4A: Host endoplasmic reticulum membrane; Single-pass type I membrane protein (Potential). Non-structural protein 4B: Host endoplasmic reticulum membrane; Multi-pass membrane protein. Non-structural protein 5A: Host endoplasmic reticulum membrane; Peripheral membrane protein. RNA-directed RNA polymerase: Host endoplasmic reticulum membrane; Single-pass type I membrane protein (Potential): P27958 |
| Total number of polymer chains | 1 |
| Total formula weight | 15149.27 |
| Authors | Liu, D.,Wang, Y.S.,Gesell, J.J.,Wyss, D.F. (deposition date: 2003-02-27, release date: 2003-03-11, Last modification date: 2022-02-23) |
| Primary citation | Liu, D.,Wang, Y.S.,Gesell, J.J.,Wyss, D.F. Solution structure and backbone dynamics of an engineered arginine-rich subdomain 2 of the hepatitis C virus NS3 RNA helicase J.Mol.Biol., 314:543-561, 2001 Cited by PubMed: 11846566DOI: 10.1006/jmbi.2001.5146 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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