1OK3

Decay accelerating factor (cd55): the structure of an intact human complement regulator.

1OK3 の概要

• エントリーDOI: 10.2210/pdb1ok3/pdb
• 関連するPDBエントリー: 1H03 1H04 1H2P 1H2Q 1M11 1NWV 1OJV 1OJW 1OJY 1OK1 1OK2
• 分子名称: COMPLEMENT DECAY-ACCELERATING FACTOR, ACETATE ION, SULFATE ION, ... (5 entities in total)
• 機能のキーワード: regulator of complement pathway, regulator of complement, decay acceleration of c3/c5 convertases, pathogen receptor, short consensus repeat domains
• 由来する生物種: HOMO SAPIENS (HUMAN)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 57794.06

構造登録者

Lukacik, P.,Roversi, P.,White, J.,Esser, D.,Smith, G.P.,Billington, J.,Williams, P.A.,Rudd, P.M.,Wormald, M.R.,Crispin, M.D.M.,Radcliffe, C.M.,Dwek, R.A.,Evans, D.J.,Morgan, B.P.,Smith, R.A.G.,Lea, S.M. (登録日: 2003-07-16, 公開日: 2004-01-07, 最終更新日: 2023-12-13)

• 主引用文献: Lukacik, P.,Roversi, P.,White, J.,Esser, D.,Smith, G.P.,Billington, J.,Williams, P.A.,Rudd, P.M.,Wormald, M.R.,Harvey, D.J.,Crispin, M.D.M.,Radcliffe, C.M.,Dwek, R.A.,Evans, D.J.,Morgan, B.P.,Smith, R.A.G.,Lea, S.M.; Complement Regulation at the Molecular Level: The Structure of Decay-Accelerating Factor; Proc.Natl.Acad.Sci.USA, 101:1279-, 2004; PubMed: 14734808; DOI: 10.1073/PNAS.0307200101

実験手法

X-RAY DIFFRACTION (2.2 Å)