1OFA

Crystal structure of the tyrosine-regulated 3-deoxy-d-arabino-heptulosonate-7-phosphate synthase from saccharomyces cerevisiae in complex with phosphoenolpyruvate and cobalt(ii)

Summary for 1OFA

• Entry DOI: 10.2210/pdb1ofa/pdb
• Related: 1HFB 1OAB 1OF6 1OF8 1OFB
• Descriptor: PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE, COBALT (II) ION, PHOSPHOENOLPYRUVATE, ... (5 entities in total)
• Functional Keywords: beta-alpha-barrel, lyase, aromatic amino-acid biosynthesis synthase, aldolase, synthetase, manganese
• Biological source: SACCHAROMYCES CEREVISIAE (BAKER'S YEAST)
• Total number of polymer chains: 2
• Total formula weight: 80324.34

Authors

Koenig, V.,Pfeil, A.,Heinrich, G.,Braus, G.H.,Schneider, T.R. (deposition date: 2003-04-09, release date: 2004-04-08, Last modification date: 2023-12-13)

• Primary citation: Koenig, V.,Pfeil, A.,Braus, G.H.,Schneider, T.R.; Substrate and Metal Complexes of 3-Deoxy-D-Arabino-Heptulosonate-7-Phosphate Synthase from Saccharomyces Cerevisiae Provide New Insights Into the Catalytic Mechanism; J.Mol.Biol., 337:675-, 2004; PubMed: 15019786; DOI: 10.1016/J.JMB.2004.01.055

Experimental method

X-RAY DIFFRACTION (2.02 Å)