1ODW
Native HIV-1 Proteinase
Summary for 1ODW
Entry DOI | 10.2210/pdb1odw/pdb |
Related | 1ODX |
Descriptor | HIV-1 PROTEASE, di-tert-butyl {iminobis[(2S,3S)-3-hydroxy-1-phenylbutane-4,2-diyl]}biscarbamate (3 entities in total) |
Functional Keywords | proteinase, retropepsin, retrovirus, hiv, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Human immunodeficiency virus 1 (HIV-1) |
Cellular location | Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P04585 |
Total number of polymer chains | 2 |
Total formula weight | 22123.15 |
Authors | Thanki, N.,Kervinen, J.,Wlodawer, A. (deposition date: 1996-09-16, release date: 1997-04-01, Last modification date: 2024-02-14) |
Primary citation | Kervinen, J.,Thanki, N.,Zdanov, A.,Tino, J.,Barrish, J.,Lin, P.F.,Colonno, R.,Riccardi, K.,Samanta, H.,Wlodawer, A. Structural Analysis of the Native and Drug-Resistant HIV-1 Proteinases Complexed with an Aminodiol Inhibitor Protein Pept.Lett., 3:399-, 1996 Cited by |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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