1OCE

ACETYLCHOLINESTERASE (E.C. 3.1.1.7) COMPLEXED WITH MF268

1OCE の概要

• エントリーDOI: 10.2210/pdb1oce/pdb
• 分子名称: ACETYLCHOLINESTERASE, CIS-2,6-DIMETHYLMORPHOLINOOCTYLCARBAMYLESEROLINE (3 entities in total)
• 機能のキーワード: hydrolase, carboxylic esterase, neurotransmitter cleavage, serine esterase
• 由来する生物種: Torpedo californica (Pacific electric ray)
• 細胞内の位置: Isoform H: Cell membrane; Lipid-anchor, GPI- anchor. Isoform T: Cell membrane; Peripheral membrane protein: P04058
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 61006.93

構造登録者

Bartolucci, C.,Perola, E.,Cellai, L.,Brufani, M.,Lamba, D. (登録日: 1998-06-12, 公開日: 1999-05-18, 最終更新日: 2023-08-09)

• 主引用文献: Bartolucci, C.,Perola, E.,Cellai, L.,Brufani, M.,Lamba, D.; "Back door" opening implied by the crystal structure of a carbamoylated acetylcholinesterase.; Biochemistry, 38:5714-5719, 1999; PubMed: 10231521; DOI: 10.1021/bi982723p

実験手法

X-RAY DIFFRACTION (2.7 Å)