1O9K
Crystal structure of the retinoblastoma tumour suppressor protein bound to E2F peptide
Summary for 1O9K
Entry DOI | 10.2210/pdb1o9k/pdb |
Related | 1AD6 1GH6 1GUX 1H24 1H25 1N4M 1PJM 2AZE |
Descriptor | RETINOBLASTOMA-ASSOCIATED PROTEIN, TRANSCRIPTION FACTOR E2F1, ... (4 entities in total) |
Functional Keywords | apoptosis, tumour suppressor, cell cycle regulation, dna-binding |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Nucleus: P06400 P06400 Q01094 |
Total number of polymer chains | 12 |
Total formula weight | 181974.62 |
Authors | Xiao, B.,Spencer, J.,Clements, A.,Ali-Khan, N.,Mittnacht, S.,Broceno, C.,Burghammer, M.,Perrakis, A.,Marmorstein, R.,Gamblin, S.J. (deposition date: 2002-12-16, release date: 2003-03-06, Last modification date: 2023-12-13) |
Primary citation | Xiao, B.,Spencer, J.,Clements, A.,Ali-Khan, N.,Mittnacht, S.,Broceno, C.,Burghammer, M.,Perrakis, A.,Marmorstein, R.,Gamblin, S.J. Crystal Structure of the Retinoblastoma Tumor Suppressor Protein Bound to E2F and the Molecular Basis of its Regulation Proc.Natl.Acad.Sci.USA, 100:2363-, 2003 Cited by PubMed: 12598654DOI: 10.1073/PNAS.0436813100 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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