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1O9K

Crystal structure of the retinoblastoma tumour suppressor protein bound to E2F peptide

Summary for 1O9K
Entry DOI10.2210/pdb1o9k/pdb
Related1AD6 1GH6 1GUX 1H24 1H25 1N4M 1PJM 2AZE
DescriptorRETINOBLASTOMA-ASSOCIATED PROTEIN, TRANSCRIPTION FACTOR E2F1, ... (4 entities in total)
Functional Keywordsapoptosis, tumour suppressor, cell cycle regulation, dna-binding
Biological sourceHOMO SAPIENS (HUMAN)
More
Cellular locationNucleus: P06400 P06400 Q01094
Total number of polymer chains12
Total formula weight181974.62
Authors
Xiao, B.,Spencer, J.,Clements, A.,Ali-Khan, N.,Mittnacht, S.,Broceno, C.,Burghammer, M.,Perrakis, A.,Marmorstein, R.,Gamblin, S.J. (deposition date: 2002-12-16, release date: 2003-03-06, Last modification date: 2023-12-13)
Primary citationXiao, B.,Spencer, J.,Clements, A.,Ali-Khan, N.,Mittnacht, S.,Broceno, C.,Burghammer, M.,Perrakis, A.,Marmorstein, R.,Gamblin, S.J.
Crystal Structure of the Retinoblastoma Tumor Suppressor Protein Bound to E2F and the Molecular Basis of its Regulation
Proc.Natl.Acad.Sci.USA, 100:2363-, 2003
Cited by
PubMed: 12598654
DOI: 10.1073/PNAS.0436813100
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.6 Å)
Structure validation

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