1O7A
Human beta-Hexosaminidase B
Summary for 1O7A
Entry DOI | 10.2210/pdb1o7a/pdb |
Related | 1QBD |
Descriptor | BETA-HEXOSAMINIDASE BETA CHAIN, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-(acetylamido)-2-deoxy-D-glucono-1,5-lactone, ... (6 entities in total) |
Functional Keywords | hydrolase, glycosyl hydrolase, hexosaminidase, lysosomal, sphingolipid degradation, sandhoff disease, ba8-barrel, glycosidase |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 6 |
Total formula weight | 359674.09 |
Authors | Maier, T.,Strater, N.,Schuette, C.,Klingenstein, R.,Sandhoff, K.,Saenger, W. (deposition date: 2002-10-29, release date: 2003-10-23, Last modification date: 2020-11-18) |
Primary citation | Maier, T.,Strater, N.,Schuette, C.,Klingenstein, R.,Sandhoff, K.,Saenger, W. The X-Ray Crystal Structure of Human Beta-Hexosaminidase B Provides New Insights Into Sandhoff Disease J.Mol.Biol., 328:669-, 2003 Cited by PubMed: 12706724DOI: 10.1016/S0022-2836(03)00311-5 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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