1O25

Crystal structure of Thymidylate Synthase Complementing Protein (TM0449) from Thermotoga maritima with dUMP at 2.4 A resolution

1O25 の概要

• エントリーDOI: 10.2210/pdb1o25/pdb
• 関連するPDBエントリー: 1O24 1O26 1O27 1O28 1O29 1O2A 1O2B
• 分子名称: Thymidylate synthase thyX, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE (3 entities in total)
• 機能のキーワード: tm0449, thymidylate synthase complementing protein, structural genomics, jcsg, joint center for structural genomics, psi, protein structure initiative, transferase
• 由来する生物種: Thermotoga maritima
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 111247.45

構造登録者

Mathews, I.I.,Deacon, A.M.,Canaves, J.M.,McMullan, D.,Lesley, S.A.,Agarwalla, S.,Kuhn, P.,Joint Center for Structural Genomics (JCSG) (登録日: 2003-02-20, 公開日: 2003-06-24, 最終更新日: 2023-09-20)

• 主引用文献: Mathews, I.I.,Deacon, A.M.,Canaves, J.M.,McMullan, D.,Lesley, S.A.,Agarwalla, S.,Kuhn, P.; Functional Analysis of Substrate and Cofactor Complex Structures of a Thymidylate Synthase-Complementing Protein; Structure, 11:677-690, 2003; PubMed: 12791256; DOI: 10.1016/S0969-2126(03)00097-2

実験手法

X-RAY DIFFRACTION (2.4 Å)