1O1S

Structure of FPT bound to isoprenoid analog 3b

Summary for 1O1S

Entry DOI	10.2210/pdb1o1s/pdb
Related	1QBQ
Descriptor	Protein farnesyltransferase alpha subunit, Protein farnesyltransferase beta subunit, ZINC ION, ... (5 entities in total)
Functional Keywords	transferase, prenyltransferase
Biological source	Rattus norvegicus (Norway rat) More
Total number of polymer chains	2
Total formula weight	92707.54
Authors	Turek-Etienne, T.C.,Strickland, C.L.,Distefano, M.D. (deposition date: 2003-01-14, release date: 2003-05-06, Last modification date: 2024-03-13)
Primary citation	Turek-Etienne, T.C.,Strickland, C.L.,Distefano, M.D. Biochemical and Structural Studies with Prenyl Diphosphate Analogues Provide Insights into Isoprenoid Recognition by Protein Farnesyl Transferase Biochemistry, 42:3716-3724, 2003 Cited by PubMed: 12667062 DOI: 10.1021/bi0266838 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation