1NYE

Crystal structure of OsmC from E. coli

1NYE の概要

• エントリーDOI: 10.2210/pdb1nye/pdb
• 分子名称: Osmotically inducible protein C (2 entities in total)
• 機能のキーワード: osmc, structural genomics, peroxiredoxin, bsgc structure funded by nih, protein structure initiative, psi, berkeley structural genomics center, unknown function
• 由来する生物種: Escherichia coli
• 細胞内の位置: Cytoplasm: P0C0L2
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 104721.50

構造登録者

Shin, D.H.,Choi, I.-G.,Busso, D.,Jancarik, J.,Yokota, H.,Kim, R.,Kim, S.-H.,Berkeley Structural Genomics Center (BSGC) (登録日: 2003-02-12, 公開日: 2004-03-02, 最終更新日: 2024-02-14)

主引用文献

Shin, D.H.,Choi, I.G.,Busso, D.,Jancarik, J.,Yokota, H.,Kim, R.,Kim, S.H.
Structure of OsmC from Escherichia coli: a salt-shock-induced protein.
Acta Crystallogr.,Sect.D, 60:903-911, 2004

PubMed Abstract: The crystal structure of an osmotically inducible protein (OsmC) from Escherichia coli has been determined at 2.4 A resolution. OsmC is a representative protein of the OsmC sequence family, which is composed of three sequence subfamilies. The structure of OsmC provides a view of a salt-shock-induced protein. Two identical monomers form a cylindrically shaped dimer in which six helices are located on the inside and two six-stranded beta-sheets wrap around these helices. Structural comparison suggests that the OsmC sequence family has a peroxiredoxin function and has a unique structure compared with other peroxiredoxin families. A detailed analysis of structures and sequence comparisons in the OsmC sequence family revealed that each subfamily has unique motifs. In addition, the molecular function of the OsmC sequence family is discussed based on structural comparisons among the subfamily members.

PubMed: 15103136
DOI: 10.1107/S0907444904005013

実験手法

X-RAY DIFFRACTION (2.4 Å)