1NXY
Crystal Structure of the complex between M182T mutant of TEM-1 and a boronic acid inhibitor (SM2)
Summary for 1NXY
Entry DOI | 10.2210/pdb1nxy/pdb |
Descriptor | Beta-lactamase TEM, POTASSIUM ION, (1R)-1-(2-THIENYLACETYLAMINO)-1-(3-CARBOXYPHENYL)METHYLBORONIC ACID, ... (4 entities in total) |
Functional Keywords | antibiotic resistance, beta-lactamase, deacylation transition-state analog, hydrolase |
Biological source | Escherichia coli |
Total number of polymer chains | 1 |
Total formula weight | 29589.28 |
Authors | Wang, X.,Minasov, G.,Blazquez, J.,Caselli, E.,Prati, F.,Shoichet, B.K. (deposition date: 2003-02-11, release date: 2003-08-26, Last modification date: 2023-08-16) |
Primary citation | Wang, X.,Minasov, G.,Blazquez, J.,Caselli, E.,Prati, F.,Shoichet, B.K. Recognition and Resistance in TEM beta-lactamase Biochemistry, 42:8434-8444, 2003 Cited by PubMed: 12859188DOI: 10.1021/bi034242y PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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