1NVQ

The Complex Structure Of Checkpoint Kinase Chk1/UCN-01

Summary for 1NVQ

Entry DOI	10.2210/pdb1nvq/pdb
Descriptor	Serine/threonine-protein kinase Chk1, Peptide ASVSA, SULFATE ION, ... (5 entities in total)
Functional Keywords	chk1-ucn-01 complex, transferase
Biological source	Homo sapiens (human)
Cellular location	Nucleus: O14757
Total number of polymer chains	2
Total formula weight	34055.04
Authors	Zhao, B.,Bower, M.J.,McDevitt, P.J.,Zhao, H.,Davis, S.T.,Johanson, K.O.,Green, S.M.,Concha, N.O.,Zhou, B.B. (deposition date: 2003-02-04, release date: 2003-04-08, Last modification date: 2023-08-16)
Primary citation	Zhao, B.,Bower, M.J.,McDevitt, P.J.,Zhao, H.,Davis, S.T.,Johanson, K.O.,Green, S.M.,Concha, N.O.,Zhou, B.B. Structural Basis for Chk1 Inhibition by UCN-01 J.Biol.Chem., 277:46609-46615, 2002 Cited by PubMed: 12244092 DOI: 10.1074/jbc.M201233200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation