1NSG

THE STRUCTURE OF THE IMMUNOPHILIN-IMMUNOSUPPRESSANT FKBP12-RAPAMYCIN COMPLEX INTERACTING WITH HUMAN FRAP

1NSG の概要

• エントリーDOI: 10.2210/pdb1nsg/pdb
• 分子名称: FK506-BINDING PROTEIN, FKBP-RAPAMYCIN ASSOCIATED PROTEIN (FRAP), C49-METHYL RAPAMYCIN, ... (4 entities in total)
• 機能のキーワード: complex (isomerase-kinase), transferase, fkbp12, frap, rapamycin, complex (isomerase-kinase) complex, complex (isomerase/kinase)
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Cytoplasm: P62942; Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side: P42345
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 24096.64

構造登録者

Liang, J.,Choi, J.,Clardy, J. (登録日: 1997-07-01, 公開日: 1998-03-18, 最終更新日: 2024-02-14)

• 主引用文献: Liang, J.,Choi, J.,Clardy, J.; Refined structure of the FKBP12-rapamycin-FRB ternary complex at 2.2 A resolution.; Acta Crystallogr.,Sect.D, 55:736-744, 1999; PubMed: 10089303; DOI: 10.1107/S0907444998014747

実験手法

X-RAY DIFFRACTION (2.2 Å)