1NSC

INFLUENZA B VIRUS NEURAMINIDASE CAN SYNTHESIZE ITS OWN INHIBITOR

1NSC の概要

• エントリーDOI: 10.2210/pdb1nsc/pdb
• 分子名称: NEURAMINIDASE, 2-acetamido-2-deoxy-beta-D-glucopyranose, N-acetyl-alpha-neuraminic acid, ... (5 entities in total)
• 機能のキーワード: hydrolase(o-glycosyl)
• 由来する生物種: Influenza B virus (STRAIN B/BEIJING/1/87)
• 細胞内の位置: Virion membrane : P27907
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 88039.70

構造登録者

Burmeister, W.P.,Ruigrok, R.W.H.,Cusack, S. (登録日: 1993-05-24, 公開日: 1993-10-31, 最終更新日: 2024-11-06)

主引用文献

Burmeister, W.P.,Henrissat, B.,Bosso, C.,Cusack, S.,Ruigrok, R.W.
Influenza B virus neuraminidase can synthesize its own inhibitor.
Structure, 1:19-26, 1993

PubMed Abstract: Neuraminidase, one of the two surface glycoproteins of influenza virus, cleaves terminal sialic acid residues from glycolipids or glycoproteins. Its crystal structure is known at high resolution, but the mechanism of glycosyl hydrolysis remains unclear.

PubMed: 8069621
DOI: 10.1016/0969-2126(93)90005-2

実験手法

X-RAY DIFFRACTION (1.7 Å)