1NRS

CRYSTALLOGRAPHIC STRUCTURES OF THROMBIN COMPLEXED WITH THROMBIN RECEPTOR PEPTIDES: EXISTENCE OF EXPECTED AND NOVEL BINDING MODES

1NRS の概要

• エントリーDOI: 10.2210/pdb1nrs/pdb
• 分子名称: ALPHA-THROMBIN (SMALL SUBUNIT), ALPHA-THROMBIN (LARGE SUBUNIT), RECEPTOR BASED PEPTIDE NRP, ... (5 entities in total)
• 機能のキーワード: serine proteinase, receptor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Secreted, extracellular space: P00734 P00734; Secreted: P09945
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 35911.88

構造登録者

Tulinsky, A.,Mathews, I.I. (登録日: 1994-01-18, 公開日: 1994-05-31, 最終更新日: 2011-07-13)

• 主引用文献: Mathews, I.I.,Padmanabhan, K.P.,Ganesh, V.,Tulinsky, A.,Ishii, M.,Chen, J.,Turck, C.W.,Coughlin, S.R.,Fenton 2nd., J.W.; Crystallographic structures of thrombin complexed with thrombin receptor peptides: existence of expected and novel binding modes.; Biochemistry, 33:3266-3279, 1994; PubMed: 8136362; DOI: 10.1021/bi00177a018

実験手法

X-RAY DIFFRACTION (2.4 Å)