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1NMZ

Crystal structure of human thymidylate kinase with NH2TMP and AppNHp

Summary for 1NMZ
Entry DOI10.2210/pdb1nmz/pdb
Descriptorsimilar to THYMIDYLATE KINASE (DTMP KINASE), MAGNESIUM ION, 3'-DEOXY-3'-AMINOTHYMIDINE MONOPHOSPHATE, ... (5 entities in total)
Functional Keywordsthymidylate kinase, p-loop, aminothymidine, transferase
Biological sourceHomo sapiens (human)
Total number of polymer chains1
Total formula weight24928.56
Authors
Ostermann, N.,Segura-Pena, D.,Meier, C.,Veit, T.,Monnerjahn, M.,Konrad, M.,Lavie, A. (deposition date: 2003-01-12, release date: 2003-03-18, Last modification date: 2024-02-14)
Primary citationOstermann, N.,Segura-Pena, D.,Meier, C.,Veit, T.,Monnerjahn, M.,Konrad, M.,Lavie, A.
Structures of human thymidylate kinase in complex with prodrugs: implications for the structure-based design of novel compounds
Biochemistry, 42:2568-2577, 2003
Cited by
PubMed: 12614151
DOI: 10.1021/bi027302t
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.75 Å)
Structure validation

217705

건을2024-03-27부터공개중

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