1NMX
Crystal structure of human thymidylate kinase with FLTMP and ADP
Summary for 1NMX
Entry DOI | 10.2210/pdb1nmx/pdb |
Descriptor | similar to THYMIDYLATE KINASE (DTMP KINASE), MAGNESIUM ION, 3'-FLUORO-3'-DEOXYTHYMIDINE MONOPHOSPHATE, ... (5 entities in total) |
Functional Keywords | thymidylate kinase, p-loop, fluorothymidine, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 24852.54 |
Authors | Ostermann, N.,Segura-Pena, D.,Meier, C.,Veit, T.,Monnerjahn, M.,Konrad, M.,Lavie, A. (deposition date: 2003-01-12, release date: 2003-03-18, Last modification date: 2024-02-14) |
Primary citation | Ostermann, N.,Segura-Pena, D.,Meier, C.,Veit, T.,Monnerjahn, M.,Konrad, M.,Lavie, A. Structures of human thymidylate kinase in complex with prodrugs: implications for the structure-based design of novel compounds Biochemistry, 42:2568-2577, 2003 Cited by PubMed: 12614151DOI: 10.1021/bi027302t PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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