1NJA

THYMIDYLATE SYNTHASE, MUTATION, N229C WITH 2'-DEOXYCYTIDINE 5'-MONOPHOSPHATE (DCMP)

1NJA の概要

• エントリーDOI: 10.2210/pdb1nja/pdb
• 分子名称: THYMIDYLATE SYNTHASE, 2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE (3 entities in total)
• 機能のキーワード: transferase, methyltransferase, nucleotide biosynthesis, transferase (methyltransferase)
• 由来する生物種: Lactobacillus casei
• 細胞内の位置: Cytoplasm: P00469
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 36926.69

構造登録者

Finer-Moore, J.,Stroud, R.M. (登録日: 1996-01-23, 公開日: 1996-07-11, 最終更新日: 2024-02-14)

• 主引用文献: Finer-Moore, J.S.,Liu, L.,Schafmeister, C.E.,Birdsall, D.L.,Mau, T.,Santi, D.V.,Stroud, R.M.; Partitioning roles of side chains in affinity, orientation, and catalysis with structures for mutant complexes: asparagine-229 in thymidylate synthase.; Biochemistry, 35:5125-5136, 1996; PubMed: 8611496; DOI: 10.1021/bi952751x

実験手法

X-RAY DIFFRACTION (2.5 Å)