1NEJ
Crystalline Human Carbonmonoxy Hemoglobin S (Liganded Sickle Cell Hemoglobin) Exhibits The R2 Quaternary State At Neutral pH In The Presence Of Polyethylene Glycol: The 2.1 Angstrom Resolution Crystal Structure
Summary for 1NEJ
Entry DOI | 10.2210/pdb1nej/pdb |
Related | 1BBB 1HHO 1K1K 1M9P 1RVW |
Descriptor | Hemoglobin alpha chain, Hemoglobin beta chain, PROTOPORPHYRIN IX CONTAINING FE, ... (5 entities in total) |
Functional Keywords | mutant human hemoglobin s[betae6v]; r2 quaternary state; human hemoglobin, oxygen storage-transport complex, oxygen storage/transport |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 64599.13 |
Authors | Patskovska, L.N.,Patskovsky, Y.V.,Almo, S.C.,Hirsch, R.E. (deposition date: 2002-12-11, release date: 2003-12-16, Last modification date: 2023-08-16) |
Primary citation | Patskovska, L.N.,Patskovsky, Y.V.,Almo, S.C.,Hirsch, R.E. COHbC and COHbS crystallize in the R2 quaternary state at neutral pH in the presence of PEG 4000. Acta Crystallogr.,Sect.D, 61:566-573, 2005 Cited by PubMed: 15858266DOI: 10.1107/S0907444905004622 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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