1NE6

Crystal structure of Sp-cAMP binding R1a subunit of cAMP-dependent protein kinase

Summary for 1NE6

• Entry DOI: 10.2210/pdb1ne6/pdb
• Related: 1CX4 1NE4 1RGS
• Descriptor: cAMP-dependent protein kinase type I-alpha regulatory chain, 6-(6-AMINO-PURIN-9-YL)-2-THIOXO-TETRAHYDRO-2-FURO[3,2-D][1,3,2]DIOXAPHOSPHININE-2,7-DIOL (3 entities in total)
• Functional Keywords: camp-dependent protein kinase, r1a subunit, camp analog, sp-camp, hydrolase
• Biological source: Bos taurus (cattle)
• Total number of polymer chains: 1
• Total formula weight: 32570.65

Authors

Wu, J.,Jones, J.M.,Xuong, N.H.,Taylor, S.S. (deposition date: 2002-12-10, release date: 2004-01-13, Last modification date: 2023-08-16)

• Primary citation: Wu, J.,Jones, J.M.,Xuong, N.H.,Eyck, L.F.,Taylor, S.S.; Crystal Structures of RIalpha Subunit of Cyclic Adenosine 5'-Monophosphate (cAMP)-Dependent Protein Kinase Complexed with (R(p))-Adenosine 3',5'-Cyclic Monophosphothioate and (S(p))-Adenosine 3',5'-Cyclic Monophosphothioate, the Phosphothioate Analogues of cAMP.; Biochemistry, 43:6620-6629, 2004; PubMed: 15157095; DOI: 10.1021/bi0302503

Experimental method

X-RAY DIFFRACTION (2.3 Å)