1ND6

Crystal Structures of Human Prostatic Acid Phosphatase in Complex with a Phosphate Ion and alpha-Benzylaminobenzylphosphonic Acid Update the Mechanistic Picture and Offer New Insights into Inhibitor Design

1ND6 の概要

• エントリーDOI: 10.2210/pdb1nd6/pdb
• 関連するPDBエントリー: 1CVI 1ND5 2HPA
• 分子名称: prostatic acid phosphatase, GLYCINE, alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (11 entities in total)
• 機能のキーワード: prostatic acid phosphatase, pap, prostate, phosphate, inhibitor, hydrolase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 169634.16

構造登録者

Ortlund, E.,LaCount, M.W.,Lebioda, L. (登録日: 2002-12-07, 公開日: 2002-12-20, 最終更新日: 2020-07-29)

• 主引用文献: Ortlund, E.,LaCount, M.W.,Lebioda, L.; Crystal structures of human prostatic acid phosphatase in complex with a phosphate ion and alpha-benzylaminobenzylphosphonic acid update the mechanistic picture and offer new insights into inhibitor design; Biochemistry, 42:383-389, 2003; PubMed: 12525165; DOI: 10.1021/bi0265067

実験手法