1NCQ
The structure of HRV14 when complexed with pleconaril, an antiviral compound
Summary for 1NCQ
Entry DOI | 10.2210/pdb1ncq/pdb |
Related | 1NA1 |
Descriptor | COAT PROTEIN VP1, COAT PROTEIN VP2, COAT PROTEIN VP3, ... (6 entities in total) |
Functional Keywords | rhinovirus 14, hrv, pleconaril, icosahedral virus, virus |
Biological source | Human rhinovirus 14 More |
Cellular location | Protein VP2: Virion. Protein VP3: Virion. Protein VP1: Virion. Protein 2B: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 2C: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3A: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3B: Virion (Potential). Picornain 3C: Host cytoplasm (Potential). RNA-directed RNA polymerase 3D-POL: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential): P03303 P03303 P03303 P03303 |
Total number of polymer chains | 4 |
Total formula weight | 94863.88 |
Authors | Zhang, Y.,Simpson, A.A.,Bator, C.M.,Chakravarty, S.,Pevear, D.C.,Skochko, G.A.,Tull, T.M.,Diana, G.,Rossmann, M.G. (deposition date: 2002-12-05, release date: 2003-12-16, Last modification date: 2024-05-22) |
Primary citation | Zhang, Y.,Simpson, A.A.,Ledford, R.M.,Bator, C.M.,Chakravarty, S.,Skochko, G.A.,Demenczuk, T.M.,Watanyar, A.,Pevear, D.C.,Rossmann, M.G. Structural and virological studies of the stages of virus replication that are affected by antirhinovirus compounds J.Virol., 78:11061-11069, 2004 Cited by PubMed: 15452226DOI: 10.1128/JVI.78.20.11061-11069.2004 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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