1NCQ

The structure of HRV14 when complexed with pleconaril, an antiviral compound

1NCQ の概要

• エントリーDOI: 10.2210/pdb1ncq/pdb
• 関連するPDBエントリー: 1NA1
• 分子名称: COAT PROTEIN VP1, COAT PROTEIN VP2, COAT PROTEIN VP3, ... (6 entities in total)
• 機能のキーワード: rhinovirus 14, hrv, pleconaril, icosahedral virus, virus
• 由来する生物種: Human rhinovirus 14; 詳細
• 細胞内の位置: Protein VP2: Virion. Protein VP3: Virion. Protein VP1: Virion. Protein 2B: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 2C: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3A: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3B: Virion (Potential). Picornain 3C: Host cytoplasm (Potential). RNA-directed RNA polymerase 3D-POL: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential): P03303 P03303 P03303 P03303
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 94863.88

構造登録者

Zhang, Y.,Simpson, A.A.,Bator, C.M.,Chakravarty, S.,Pevear, D.C.,Skochko, G.A.,Tull, T.M.,Diana, G.,Rossmann, M.G. (登録日: 2002-12-05, 公開日: 2003-12-16, 最終更新日: 2024-05-22)

• 主引用文献: Zhang, Y.,Simpson, A.A.,Ledford, R.M.,Bator, C.M.,Chakravarty, S.,Skochko, G.A.,Demenczuk, T.M.,Watanyar, A.,Pevear, D.C.,Rossmann, M.G.; Structural and virological studies of the stages of virus replication that are affected by antirhinovirus compounds; J.Virol., 78:11061-11069, 2004; PubMed: 15452226; DOI: 10.1128/JVI.78.20.11061-11069.2004

実験手法

X-RAY DIFFRACTION (2.5 Å)