1NAX

Thyroid receptor beta1 in complex with a beta-selective ligand

Summary for 1NAX

Entry DOI	10.2210/pdb1nax/pdb
Related	1NAV
Descriptor	Thyroid hormone receptor beta-1, {3,5-DICHLORO-4-[4-HYDROXY-3-(PROPAN-2-YL)PHENOXY]PHENYL}ACETIC ACID (3 entities in total)
Functional Keywords	nuclear receptor, thyroid receptor, complex, membrane protein
Biological source	Homo sapiens (human)
Cellular location	Nucleus: P10828
Total number of polymer chains	1
Total formula weight	28822.21
Authors	Ye, L.,Li, Y.L.,Mellstrom, K.,Mellin, C.,Bladh, L.G.,Koehler, K.,Garg, N.,Garcia Collazo, A.M.,Litten, C.,Husman, B.,Persson, K.,Ljunggren, J.,Grover, G.,Sleph, P.G.,George, R.,Malm, J. (deposition date: 2002-11-29, release date: 2003-06-17, Last modification date: 2024-02-14)
Primary citation	Ye, L.,Li, Y.L.,Mellstrom, K.,Mellin, C.,Bladh, L.G.,Koehler, K.,Garg, N.,Garcia Collazo, A.M.,Litten, C.,Husman, B.,Persson, K.,Ljunggren, J.,Grover, G.,Sleph, P.G.,George, R.,Malm, J. Thyroid receptor ligands. 1. Agonist ligands selective for the thyroid receptor beta1. J.Med.Chem., 46:1580-1588, 2003 Cited by PubMed: 12699376 DOI: 10.1021/jm021080f PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation