1N6V

Average structure of the interferon-binding ectodomain of the human type I interferon receptor

Summary for 1N6V

• Entry DOI: 10.2210/pdb1n6v/pdb
• Related: 1N6U
• NMR Information: BMRB: 5049
• Descriptor: Interferon-alpha/beta receptor beta chain (1 entity in total)
• Functional Keywords: immunoglobulin fold, fibronectin fold, two-domain structure, immune system
• Biological source: Homo sapiens (human)
• Cellular location: Isoform 1: Membrane; Single-pass type I membrane protein. Isoform 2: Membrane; Single-pass type I membrane protein. Isoform 3: Secreted: P48551
• Total number of polymer chains: 1
• Total formula weight: 24323.44

Authors

Chill, J.H.,Quadt, S.R.,Levy, R.,Schreiber, G.,Anglister, J. (deposition date: 2002-11-12, release date: 2003-07-15, Last modification date: 2022-02-23)

• Primary citation: Chill, J.H.,Quadt, S.R.,Levy, R.,Schreiber, G.,Anglister, J.; The human type I interferon receptor. NMR structure reveals the molecular basis of ligand binding.; Structure, 11:791-802, 2003; PubMed: 12842042; DOI: 10.1016/S0969-2126(03)00120-5

Experimental method

SOLUTION NMR