1N5A

Crystal structure of the Murine class I Major Histocompatibility Complex of H-2DB, B2-Microglobulin, and A 9-Residue immunodominant peptide epitope gp33 derived from LCMV

1N5A の概要

• エントリーDOI: 10.2210/pdb1n5a/pdb
• 関連するPDBエントリー: 1FG2
• 分子名称: H-2 class I histocompatibility antigen, D-B alpha chain, Beta-2-microglobulin, nonameric peptide, gp33 derived from lymphocytic choriomeningitis virus, ... (4 entities in total)
• 機能のキーワード: murine mhc, viral escape, lcmv, immunodominant epitope, immune system
• 由来する生物種: Mus musculus (house mouse); 詳細
• 細胞内の位置: Membrane; Single-pass type I membrane protein: P01899; Secreted: P01887
• タンパク質・核酸の鎖数: 12
• 化学式量合計: 179349.18

構造登録者

Achour, A.,Michaelsson, J.,Harris, R.A.,Odeberg, J.,Grufman, P.,Sandberg, J.K.,Levitsky, V.,Karre, K.,Sandalova, T.,Schneider, G. (登録日: 2002-11-05, 公開日: 2003-01-07, 最終更新日: 2021-10-27)

• 主引用文献: Achour, A.,Michaelsson, J.,Harris, R.A.,Odeberg, J.,Grufman, P.,Sandberg, J.K.,Levitsky, V.,Karre, K.,Sandalova, T.,Schneider, G.; A Structural Basis for LCMV Immune Evasion. Subversion of H-2D(b) and H-2K(b) Presentation of gp33 Revealed by Comparative Crystal Structure Analyses.; Immunity, 17:757-768, 2002; PubMed: 12479822; DOI: 10.1016/S1074-7613(02)00478-8

実験手法

X-RAY DIFFRACTION (2.85 Å)