1N2O

Crystal Structure of Pantothenate Synthetase from M. tuberculosis, low occupancy of beta-alanine at the pantoate binding sites

1N2O の概要

• エントリーDOI: 10.2210/pdb1n2o/pdb
• 関連するPDBエントリー: 1MOP 1N2B 1N2E 1N2G 1N2H 1N2I 1N2J
• 分子名称: pantothenate synthetase, SULFATE ION, BETA-ALANINE, ... (4 entities in total)
• 機能のキーワード: structural genomics, rossmann fold, dimer, intersubunit beta sheet, psi, protein structure initiative, tb structural genomics consortium, tbsgc, ligase
• 由来する生物種: Mycobacterium tuberculosis
• 細胞内の位置: Cytoplasm (Potential): P0A5R0
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 63370.51

構造登録者

Wang, S.,Eisenberg, D.,TB Structural Genomics Consortium (TBSGC) (登録日: 2002-10-23, 公開日: 2003-04-23, 最終更新日: 2024-02-14)

• 主引用文献: Wang, S.,Eisenberg, D.; Crystal structures of a pantothenate synthetase from M. tuberculosis and its complexes with substrates and a reaction intermediate; Protein Sci., 12:1097-1108, 2003; PubMed: 12717031; DOI: 10.1110/ps.0241803

実験手法

X-RAY DIFFRACTION (2.1 Å)