1N17

Structure and Dynamics of Thioguanine-modified Duplex DNA

Summary for 1N17

• Entry DOI: 10.2210/pdb1n17/pdb
• Related: 1N14
• Descriptor: 5'-D(*GP*CP*TP*AP*AP*GP*(S6G)P*AP*AP*AP*GP*CP*C)-3', 5'-D(*GP*GP*CP*TP*TP*TP*CP*CP*TP*TP*AP*GP*C)-3' (2 entities in total)
• Functional Keywords: thioguanine, 6-mercapto purine, anti-cancer therapy, dna
• Total number of polymer chains: 2
• Total formula weight: 7959.26

Authors

Somerville, L.,Krynetski, E.Y.,Krynetskaia, N.F.,Beger, R.D.,Zhang, W.,Marhefka, C.A.,Evans, W.E.,Kriwacki, R.W. (deposition date: 2002-10-16, release date: 2002-10-23, Last modification date: 2022-02-23)

• Primary citation: Somerville, L.,Krynetski, E.Y.,Krynetskaia, N.F.,Beger, R.D.,Zhang, W.,Marhefka, C.A.,Evans, W.E.,Kriwacki, R.W.; Structure and dynamics of thioguanine-modified duplex DNA; J.Biol.Chem., 278:1005-1011, 2003; PubMed: 12401802; DOI: 10.1074/jbc.M204243200

Experimental method

SOLUTION NMR