1MWE

THE X-RAY STRUCTURE OF A COMPLEX OF TERN N9 INFLUENZA VIRUS NEURAMINIDASE COMPLEXED WITH SIALIC ACID AT 4 DEGREES C REVEALING A SECOND SIALIC ACID BINDING SITE

1MWE の概要

• エントリーDOI: 10.2210/pdb1mwe/pdb
• 分子名称: NEURAMINIDASE, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• 機能のキーワード: hydrolase, neuraminidase, avian influenza, sialic acid binding, hemagglutination site, heme absorbing site
• 由来する生物種: Influenza A virus
• 細胞内の位置: Virion membrane (By similarity): P03472
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 46645.48

構造登録者

Varghese, J.N. (登録日: 1997-08-27, 公開日: 1998-03-04, 最終更新日: 2024-04-03)

• 主引用文献: Varghese, J.N.,Colman, P.M.,van Donkelaar, A.,Blick, T.J.,Sahasrabudhe, A.,McKimm-Breschkin, J.L.; Structural evidence for a second sialic acid binding site in avian influenza virus neuraminidases.; Proc.Natl.Acad.Sci.USA, 94:11808-11812, 1997; PubMed: 9342319; DOI: 10.1073/pnas.94.22.11808

実験手法

X-RAY DIFFRACTION (1.7 Å)