1MUI
Crystal structure of HIV-1 protease complexed with Lopinavir.
Summary for 1MUI
Entry DOI | 10.2210/pdb1mui/pdb |
Descriptor | protease, N-{1-BENZYL-4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-5-PHENYL-PENTYL}-3-METHYL-2-(2-OXO-TETRAHYDRO-PYRIMIDIN-1-YL)-BUTYRAMIDE (2 entities in total) |
Functional Keywords | hydrolase |
Biological source | Human immunodeficiency virus 1 |
Total number of polymer chains | 2 |
Total formula weight | 22236.31 |
Authors | Stoll, V.,Qin, W.,Stewart, K.D.,Jakob, C.,Park, C.,Walter, K.,Simmer, R.L.,Helfrich, R.,Bussiere, D.,Kao, J.,Kempf, D.,Sham, H.L.,Norbeck, D.W. (deposition date: 2002-09-23, release date: 2002-10-23, Last modification date: 2024-02-14) |
Primary citation | Stoll, V.,Qin, W.,Stewart, K.D.,Jakob, C.,Park, C.,Walter, K.,Simmer, R.L.,Helfrich, R.,Bussiere, D.,Kao, J.,Kempf, D.,Sham, H.L.,Norbeck, D.W. X-ray Crystallographic Structure of ABT-378 (Lopinavir) Bound to HIV-1 Protease BIOORG.MED.CHEM., 10:2803-2806, 2002 Cited by PubMed: 12057670DOI: 10.1016/S0968-0896(02)00051-2 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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