1MO2
Thioesterase Domain from 6-Deoxyerythronolide Synthase (DEBS TE), pH 8.5
Summary for 1MO2
Entry DOI | 10.2210/pdb1mo2/pdb |
Related | 1KEZ 1MN6 1MNA 1MNQ |
Descriptor | Erythronolide synthase, modules 5 and 6 (2 entities in total) |
Functional Keywords | thioesterase, polyketide synthase, open substrate channel, te, pks, alpha beta hydrolase, 6-deoxyerythronolide, picromycin, pikromycin, erythromycin, transferase |
Biological source | Saccharopolyspora erythraea |
Total number of polymer chains | 2 |
Total formula weight | 62567.80 |
Authors | Tsai, S.-C.,Lu, H.,Cane, D.E.,Khosla, C.,Stroud, R.M. (deposition date: 2002-09-05, release date: 2003-02-04, Last modification date: 2024-02-14) |
Primary citation | Tsai, S.-C.,Lu, H.,Cane, D.E.,Khosla, C.,Stroud, R.M. Insights into channel architecture and substrate specificity from crystal structures of two macrocycle-forming thioesterases of modular polyketide synthases Biochemistry, 41:12598-12606, 2002 Cited by PubMed: 12379102DOI: 10.1021/bi0260177 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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