1ML6

Crystal Structure of mGSTA2-2 in Complex with the Glutathione Conjugate of Benzo[a]pyrene-7(R),8(S)-Diol-9(S),10(R)-Epoxide

Summary for 1ML6

Entry DOI	10.2210/pdb1ml6/pdb
Related	1F3A 1F3B
Descriptor	Glutathione S-Transferase GT41A, 2-AMINO-4-[1-(CARBOXYMETHYL-CARBAMOYL)-2-(9-HYDROXY-7,8-DIOXO-7,8,9,10-TETRAHYDRO-BENZO[DEF]CHRYSEN-10-YLSULFANYL)-ETHYLCARBAMOYL]-BUTYRIC ACID, ISOPROPYL ALCOHOL, ... (4 entities in total)
Functional Keywords	gst detoxification, mgsta2-2, transferase
Biological source	Mus musculus (house mouse)
Total number of polymer chains	2
Total formula weight	52243.02
Authors	Gu, Y.,Xiao, B.,Wargo, H.L.,Bucher, M.H.,Singh, S.V.,Ji, X. (deposition date: 2002-08-30, release date: 2003-04-15, Last modification date: 2023-11-15)
Primary citation	Gu, Y.,Xiao, B.,Wargo, H.L.,Bucher, M.H.,Singh, S.V.,Ji, X. Residues 207, 216, and 221 and the catalytic activity of mGSTA1-1 and mGSTA2-2 toward benzo[a]pyrene-(7R,8S)-diol-(9S,10R)-epoxide Biochemistry, 42:917-921, 2003 Cited by PubMed: 12549910 DOI: 10.1021/bi026778+ PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation