1MK7
CRYSTAL STRUCTURE OF AN INTEGRIN BETA3-TALIN CHIMERA
Summary for 1MK7
Entry DOI | 10.2210/pdb1mk7/pdb |
Related | 1MIX 1MIZ 1MK9 |
Descriptor | Integrin Beta3, TALIN (3 entities in total) |
Functional Keywords | focal adhesion, integrin binding, ferm domain, cytoskeleton, npxy motif, ptb domain, structural protein |
Biological source | Homo sapiens (human) More |
Cellular location | Membrane; Single-pass type I membrane protein: P05106 Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side: P54939 |
Total number of polymer chains | 4 |
Total formula weight | 47831.14 |
Authors | Garcia-Alvarez, B.,De Pereda, J.M.,Calderwood, D.A.,Ulmer, T.S.,Critchley, D.,Campbell, I.D.,Ginsberg, M.H.,Liddington, R.C. (deposition date: 2002-08-28, release date: 2003-01-28, Last modification date: 2011-07-13) |
Primary citation | Garcia-Alvarez, B.,De Pereda, J.M.,Calderwood, D.A.,Ulmer, T.S.,Critchley, D.,Campbell, I.D.,Ginsberg, M.H.,Liddington, R.C. Structural Determinants of Integrin Recognition by Talin Mol.Cell, 11:49-58, 2003 Cited by PubMed: 12535520DOI: 10.1016/S1097-2765(02)00823-7 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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