1MIU

Structure of a BRCA2-DSS1 complex

Summary for 1MIU

Entry DOI	10.2210/pdb1miu/pdb
Descriptor	Deleted in split hand/split foot protein 1, Breast Cancer type 2 susceptibility protein, MERCURY (II) ION (3 entities in total)
Functional Keywords	tumor suppressor, breast cancer susceptibility, dna-binding, gene regulation-antitumor protein complex, gene regulation/antitumor protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	2
Total formula weight	92638.12
Authors	Yang, H.,Jeffrey, P.D.,Miller, J.,Kinnucan, E.,Sun, Y.,Thoma, N.H.,Zheng, N.,Chen, P.L.,Lee, W.H.,Pavletich, N.P. (deposition date: 2002-08-23, release date: 2002-09-25, Last modification date: 2024-02-14)
Primary citation	Yang, H.,Jeffrey, P.D.,Miller, J.,Kinnucan, E.,Sun, Y.,Thoma, N.H.,Zheng, N.,Chen, P.L.,Lee, W.H.,Pavletich, N.P. BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure Science, 297:1837-1848, 2002 Cited by PubMed: 12228710 DOI: 10.1126/science.297.5588.1837 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.1 Å)

Structure validation