1MIU
Structure of a BRCA2-DSS1 complex
Summary for 1MIU
Entry DOI | 10.2210/pdb1miu/pdb |
Descriptor | Deleted in split hand/split foot protein 1, Breast Cancer type 2 susceptibility protein, MERCURY (II) ION (3 entities in total) |
Functional Keywords | tumor suppressor, breast cancer susceptibility, dna-binding, gene regulation-antitumor protein complex, gene regulation/antitumor protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 92638.12 |
Authors | Yang, H.,Jeffrey, P.D.,Miller, J.,Kinnucan, E.,Sun, Y.,Thoma, N.H.,Zheng, N.,Chen, P.L.,Lee, W.H.,Pavletich, N.P. (deposition date: 2002-08-23, release date: 2002-09-25, Last modification date: 2024-02-14) |
Primary citation | Yang, H.,Jeffrey, P.D.,Miller, J.,Kinnucan, E.,Sun, Y.,Thoma, N.H.,Zheng, N.,Chen, P.L.,Lee, W.H.,Pavletich, N.P. BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure Science, 297:1837-1848, 2002 Cited by PubMed: 12228710DOI: 10.1126/science.297.5588.1837 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.1 Å) |
Structure validation
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