1MIU

Structure of a BRCA2-DSS1 complex

1MIU の概要

• エントリーDOI: 10.2210/pdb1miu/pdb
• 分子名称: Deleted in split hand/split foot protein 1, Breast Cancer type 2 susceptibility protein, MERCURY (II) ION (3 entities in total)
• 機能のキーワード: tumor suppressor, breast cancer susceptibility, dna-binding, gene regulation-antitumor protein complex, gene regulation/antitumor protein
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 92638.12

構造登録者

Yang, H.,Jeffrey, P.D.,Miller, J.,Kinnucan, E.,Sun, Y.,Thoma, N.H.,Zheng, N.,Chen, P.L.,Lee, W.H.,Pavletich, N.P. (登録日: 2002-08-23, 公開日: 2002-09-25, 最終更新日: 2024-02-14)

• 主引用文献: Yang, H.,Jeffrey, P.D.,Miller, J.,Kinnucan, E.,Sun, Y.,Thoma, N.H.,Zheng, N.,Chen, P.L.,Lee, W.H.,Pavletich, N.P.; BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure; Science, 297:1837-1848, 2002; PubMed: 12228710; DOI: 10.1126/science.297.5588.1837

実験手法

X-RAY DIFFRACTION (3.1 Å)