1MHK

Crystal Structure Analysis of a 26mer RNA molecule, representing a new RNA motif, the hook-turn

Summary for 1MHK

Entry DOI	10.2210/pdb1mhk/pdb
Descriptor	RNA 12-mer BCh12, RNA 14-mer BCh12, BROMIDE ION, ... (4 entities in total)
Functional Keywords	helix, 180 degree turn, rna
Total number of polymer chains	2
Total formula weight	8369.95
Authors	Szep, S.,Wang, J.,Moore, P.B. (deposition date: 2002-08-20, release date: 2002-09-06, Last modification date: 2024-02-14)
Primary citation	Szep, S.,Wang, J.,Moore, P.B. The crystal structure of a 26-nucleotide RNA containing a hook-turn RNA, 9:44-51, 2003 Cited by PubMed Abstract: A crystal structure has been obtained for a 26-nucleotide RNA that contains the loop E sequence from Chromatium minutissimum. Rather than having a loop E-like conformation, it consists of an A-form helix that splits into two separate strands following a sheared A-G base pair. The backbone of the strand containing the G of the A-G pair makes a turn of almost 180 degrees in the space of two nucleotides, and then interacts with the minor groove of the helix from which it originates. Similar structures, which we call hook-turns, occur in 16S and 23S rRNAs. They are found at places where the two strands of a helix separate at an A/G juxtaposition to interact with other sequences. PubMed: 12554875 DOI: 10.1261/rna.2107303 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation